Peutz Jeghers syndrome with multiple intussusceptions

Peutz Jegher’s syndrome is a rare autosomal dominant disorder characterized by the development of hamartomatous polyps and mucocutaneous melanin pigmentation. This case report shows an adult Indian female with intestinal obstruction due to multiple intussusceptions that were caused polyp syndrome. A 32-year-old presented surgical emergency complaints colicky abdominal pain, vomiting melena positive family history for On examination, mass was palpable in her right lumbar area per rectal examination showed ballooning blood staining. She provisionally diagnosed intussusception ultrasound imaging abdomen also features suggestive intussusception. underwent laparotomy resection anastomosis involved segment jejunum limited hemicolectomy. Intraoperative findings both large small bowels along which seen be histopathological studies. The postoperative period uneventful during review she healthy. Intussusception major complication it can prevented regular surveillance known cases. should kept mind as first differential diagnosis when these patients present acute abdomen. investigation choice that’s preferred cross sectional gastrointestinal tract confirm diagnosis. Periodic essential those or mutation STK11 (LKB1) gene.